Protein Details: Aquaglyceroporin

Protein ID

ICDB_Pro_0004

Protein Name

Aquaglyceroporin

Gene Name

AQP; TGME49_215450

Organism

Toxoplasma gondii (strain ATCC 50611 / Me49)

Length

263 amino acids

AlphaFoldDB

AF-A0A125YZH9-F1-model_v4.pdb

Function

Mediates water and glycerol transport across cell membranes. Permeable to selected sugar alcohols of up to five carbons and urea. Permeable to methylamine/methylammonium.

Sequence

MDQFVFSGGSEGGGELGGDRERDSLTPELGRFEHLIFNMQKYFCEFFAALVIVSAVAFGLAKEGGAQAAPLSITSTIFALITLFKDISGAHFNPAVSCTIYMTDPRFTLVDLLCYVAAQLIGGTVGAFIGYGIMGKALDILPLDPGMSASRQLFHEVIPTMVMIYAVLVLVFGYGVMWELTVPFVVGACVLAGAFAGATMNPAVTFGIFISNICTKNTNIDVAALLVTLFGPFLGAMFAFLGYVGTHAYHNPVPLRFLNFRGL

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1016/s0014-5793(03)01313-9; 10.1111/j.1365-2958.2006.05325.x; 10.1111/j.1365-2958.2010.07165.x

RefSeq

XP_002370864.1